Visual acuity improvement in patients diagnosed with noninfectious intermediate uveitis treated with intraocular triamcinolone acetonide

Abstract

The aim of the study was to determine the effectiveness of intravitreal triamcinolone acetonide in improving the visual acuity, three months after treatment. The objectives of the study were to perform a baseline evaluation of the patients enrolled in the study, to perform intraocular injections with triamcinolone acetonide and to evaluate the best corrected visual acuity three months after the treatment. Fifty patients diagnosed with noninfectious intermediate uveitis were treated with intravitreal injection of four mg triamcinolone acetonide. The patients were divided into two study arms, twenty-three patients were subjected to intraocular injection with Triamcinolone acetonide, the rest, twenty-seven were subjected to intraocular injection with Triamcinolone acetonide and general cortisone administration. Best corrected visual acuity was determined three months after treatment. Globally, for all fifty patients, the mean ±SD visual acuity gain was 0.29 ±0.27 LogMAR. This study proves that intraocular cortisone administration has a positive effect on visual acuity that lasts for at least three months period.