Applications of Human Amniotic Membrane in Oral Medicine

Abstract

The Regenerative Medicine has become a contemporary reality, which is why the current research in this field is no longer and attractive idea, but a veritable demonstrated truth. It includes a number of technologies based on the biology and physiology of embryonic stem cells and human amniotic membrane (hAM) transplantation.Aim and objectives: The aim of the study is to summarize the way in which pathologies with oral manifestations were treated by applying different forms of hAM. The properties of the hAM described over time and subject to many contradictions of interpretation, thus acquire a practical foundation, being supported only by the results extracted from clinical studies carried out on human subjects. Material and Methods: Following the research, 20 scientific articles were included. After applying the exclusion criteria, 9 articles remained. Results: hAM was used in 82 patients with variable age ranges. The galenic form of hAM identified in all 9 studies was represented by the tissue film (patch). Conclusions: hAM has been successfully used in reconstructive surgery protocols. It`s properties can be defined as theories with a proven medical foundation, even if the number of relevant studies in this study is not large and the number of patients is relatively small.