Recent Advances Regarding the Phytochemical and Therapeutic Uses of Ribes Nigrum Leaves

Abstract

 1.Background/Objectives: This review examines the phytochemical composition and therapeutic effects of Ribes nigrum (blackcurrant). Rich in anthocyanins, flavonoids, polyphenols, and essential fatty acids, it exhibits antioxidant, anti-inflammatory, antimicrobial, and cardioprotective properties, highlighting its medical potential.   2. Methods:A systematic analysis of recent in vitro, in vivo, and clinical studies was conducted to evaluate its pharmacological effects. The review focuses on its role in inflammation reduction, oxidative stress prevention, metabolic regulation, anticancer activity, and antimicrobial defense. Extraction methods and key bioactive compounds were also assessed. 3.Results: Ribes nigrum demonstrates strong anti-inflammatory effects by inhibiting pro-inflammatory cytokines and enzymes. Its antioxidant properties help reduces oxidative stress. Metabolic benefits include cholesterol regulation, improved glucose metabolism, and cardiovascular protection. Studies suggest its potential anticancer effects through apoptosis induction in cancer cells. Additionally, its antimicrobial and antiviral properties support its use in treating infections and maintaining oral health. 4.Conclusion: The findings confirm Ribes nigrum’s therapeutic value, supporting its traditional medicinal applications and future pharmaceutical development. Further research is needed to explore its long-term clinical benefits, optimize extraction methods, and develop standardized medicinal formulations.